Safety and Performance of the CG-100 in Patients Undergoing Colorectal Surgery.

Inclusion Criteria: 1. The patient is willing to comply with protocol-specified follow-up evaluations 2. Patient 22-75 years of age at screening 3. The patient is scheduled to undergo an elective colorectal surgery (open, laparoscopic, or robotic) which will require the creation of an anastomosis, maximally 20 cm proximal from the anal verge 4. The patient or legally authorized representative, has been informed of the nature of the study, agrees to its provisions and has provided written informed consent, approved by the appropriate Medical Ethics Committee (EC) or Institutional Review Board (IRB). Exclusion Criteria: Preoperative 1. Pregnant or nursing female subjects. Female subjects of child-bearing potential must have a negative pregnancy test done within 7 days prior to surgical procedure per site standard test. 2. Patient surgical treatment is acute (not elective) 3. Patient has local or systemic infection at the time of intervention (e.g., peritonitis) 4. Major surgical or interventional procedures within 30 days prior to this study or planned surgical or interventional procedures within 30 days of entry into this study 5. Patients with ASA classification \> 3 6. Albumin \< 30 g/liter 7. Patient has a diagnosis of bowel obstruction, bowel strangulation, peritonitis, bowel perforation, ischemic bowel, carcinomatosis or extensively spread inflammatory bowel disease 8. BMI ≥ 40 9. Subject is going through another surgical procedure (other than ileostomy or adhesiolysis) during the surgery. 10. Patient is participating in another clinical trial within 30 days of screening 11. Patient has been taking regular steroid medication in the last 6 months. 12. Patient has contraindications to general anesthesia 13. Patient has preexisting sphincter problems 14. Patient has evidence of extensive local disease in the pelvis 15. Any condition which in the opinion of the investigator may jeopardize the patient's safe participation Intraoperative (prior to device deployment) 16. Anastomosis is located more than 20 cm from the anal verge 17. Internal diameter lumen of the colon is smaller than 25 mm or larger than 34 mm 18. Blood loss (\> 500 cc) 19. Anastomosis was not performed for any reason other than consequences as a result of use of the study device -