SUNCIST: A Study of Calmangafodipir in Healthy Japanese and Caucasian Subjects

Inclusion Criteria: * BMI within 18.0 to 30.0 kg/m2 and body weight not less than 50 kg * Blood pressure between 90 and 140 mmHg systolic, and no higher than 90 mmHg diastolic * Non-smoker or not smoking for at least 12 months * Be first generation Japanese (For Group 1 only), defined as: 1. Born in Japan 2. Has 2 Japanese biological parents and 4 Japanese biological grandparents 3. Has lived outside of Japan for less than 5 years 4. Has made no significant changes in lifestyle, including diet, since leaving Japan Exclusion Criteria: * Clinically significant abnormal values for hematology, clinical chemistry, urinalysis, physical exam, vital signs, or electrocardiogram at screening * Has a history of human immunodeficiency virus (HIV) antibody positive, or tests positive for HIV; has a history of hepatitis B surface antigen (HBsAg) or hepatitis C antibody (anti-HCV) positive, or other clinically active liver disease, or tests positive for HBsAg or anti-HCV at Screening. * Has a history of drug or alcohol abuse * Has previously received calmangafodipir or mangafodipir * Welders, mine workers, or other workers in occupations (current or past) where high manganese exposure is likely