Humanin Isoforms in Cardiac Muscle and Blood Plasma and Major Complications After Cardiac Operation

Overview

Objective of the study is to clarify humanin-like peptide concentration in myocard tissue and in blood and to study if its concentration level is related to early complication occurrence and frequency after cardiac operation. Hypothesis of the study is that previously described elements are related to each other.

Data collection: Historical medical and preoperative data, operation data (type of operation performed and its details), detailed postoperative course (occurrence of complications). Specimen collection: * Tissue sample is taken during the operation from the right atrial appendage of the heart and the sample is frozen at -80 C. * Blood samples are taken just before the operation, one hour after aortic cross-clamp removal and the next morning after the operation. Samples are processed and blood plasma is frozen at -80 C.

Conditions

Eligibility

Locations (2)

Outcomes