Desaturation Validation of INVSENSOR00012

Inclusion Criteria: * Subject is 18-50 years of age. * Subject weighs a minimum of 110 lbs and no more than 250 lbs unless subject is over 6 feet tall. * Hemoglobin value is greater than or equal to 11 g/dL. * Baseline heart rate ≥ 45 bpm and ≤ 85 bpm. * Carbon monoxide (CO) value ≤ 2.0% fractional carboxyhemoglobin (FCOHb) * Subject has a physical status of American Society of Anesthesiology Class I; Healthy subjects without any systemic disease at all. American Society of Anesthesiology Class II; subjects with mild systemic disease (ASA I or II) as it applies to the systemic disease portion of the classification. * Systolic Blood Pressure ≤ 140 mmHg and Diastolic Blood Pressure ≤ 90 mmHg. * Subject is able to read and communicate in English and understands the study and risks involved. Exclusion Criteria: * Subject is pregnant. * Subject smokes (smoking includes e-cigarette use). * Subject has a BMI \> 35 and has been classified as morbidly obese or at an increased risk for participation by a medical professional. * Subject has open wounds, inflamed tattoos or piercings, visible healing wounds. * Subject experiences frequent or severe headaches and/or migraine headaches. * Subject has known drug or alcohol abuse and/or use of recreational drugs. * Subject has experienced a concussion or head injury with loss of consciousness within the last year. * Subject has any chronic bleeding disorders (i.e. hemophilia). * Subject has any history of a stroke, myocardial infarction, seizures or heart attack. * Subject has any cancer or history of cancer (not including skin cancer). * Subject has a chronic neurological disease (i.e. multiple sclerosis, Huntington's Disease). * Subject has any cardiac dysrhythmia(s) (i.e. atrial fibrillation) and has not received clearance by their physician to participate. * Subject has a known neurological and/or psychiatric disorder (i.e. schizophrenia, bipolar disorder) that interferes with the subject's level of consciousness. * Subject has any medical condition which in the judgment of the investigator and/or medical staff, renders them ineligible for participation in this study (Discretion of investigator). * Subject has Wolff-Parkinson-White Syndrome or Stokes-Adams Syndrome. * Subject who has taken anticoagulant medication within the last 30 days. * Subject has taken opioid pain medication within 24 hours of start of study. * Subject has either signs or history of peripheral ischemia/carpal tunnel syndrome. * Subject has had invasive surgery within the past year- including but not limited to major dental surgery, gallbladder, heart, appendix, major fracture repairs (involving plates/ screws), jaw surgery, urinary tract surgery, plastic surgery, major ears, nose and throat (ENT) surgery, joint replacement or gynecological surgeries, heart surgery or thoracic surgery. * Subject has donated blood within the past 30 days. * Subject has symptoms of congestion, head colds, flu or other illnesses. * Subject experiences claustrophobia or has generalized anxiety disorder. * Subject has been in severe car accident(s) or a similar type of accident(s) requiring hospitalization within the last 12 months. * Subject has chronic unresolved asthma, lung disease or respiratory disease. * Subject is allergic to lidocaine, latex, adhesives, or plastic. * Subject has heart conditions, insulin-dependent Diabetes or uncontrolled hypertension. * Subject has given vaginal delivery, had a pregnancy terminated, a miscarriage with hospitalization, or had a C-section within the last 6 months. * Subject intends to participate in any heavy lifting, repetitive movement of their wrist (including riding a motorcycle) or exercise (working out, riding a bike, riding a skate board etc.), or any activity that will put additional stress on the wrist within 24 hours of the study. * Discretion of investigator/study staff.