Long-term conventional treatment of chronic hypoparathyroidism does not fully restore calcium homeostasis leading to increased morbidity, emergency events and reduced subjective health status. To further investigate general morbidity, hypocalcemic events, subjective and daily life performance in patients with chronic hypoparathyroidism a disease specific questionnaire, as well as the SF-36 are handed out.
Design: In a cross-sectional trial the subjective health status and burden of illness in patients with chronic hypoparathyroidism will be evaluated by using a disease specific questionnaire as well as the SF-36. Patients: Patients will be recruited out of the patient population of the participating five medical centers. Statistical Analysis: Documentation and analysis will be performed at the Department of Medicine I, Endocrine and Diabetes Unit, University of Würzburg, Germany. Data will be documented after pseudonymisation in a data base. For further analysis data will be compared to sex- and age-matched controls.
Study Type
OBSERVATIONAL
Enrollment
205
Endokrinologie in Charlottenburg
Berlin, Germany
Charite Berlin
Berlin, Germany
Ludwig-Maximilians-Universität
Munich, Germany
University Hospital Rostock
Rostock, Germany
Burden of illness
Assessment of the burden of illness due to chronic hypoparathyroidism using a disease specific questionnaire to further investigate impairment in daily and professional life in comparison to the general German population (DEGS1, SHIP-2).
Time frame: 12 - 24 months
Hypocalcemia
documentation of frequency of hypocalcemia under standard treatment
Time frame: 12 - 24 months
Psychological disorders
documentation of frequency of anxiety and depression under standard treatment
Time frame: 12 - 24 months
Subjective Health Status
Assessment of the subjective health status due to chronic hypoparathyroidism by Assessment of subjective health status in patients with chronic hypoparathyroidism
Time frame: 12-24 months
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Dept. of Endocrinology and Diabetology, Dept. of Medicine I, University Hospital Wuerzburg
Würzburg, Germany