Impact of Preoperative Single Corticosteroid Flash on Morbidity After Colorectal Resection: Monocentric Prospective Pilot Study

Inclusion Criteria: * Adult patient * Patient undergoing elective colorectal surgery (diverticulitis, malignant or benign tumor, inflammatory intestinal disease, re-establishing continuity, endometriosis, or other) * Bowel continuity is restored immediately after surgery, with or without a protective stoma. * Patient with proper understanding who has been informed about the study, and who has consented to being part of the study Exclusion Criteria: * Adult under guardianship * Patient who is not covered under the national health system * Women who are pregnant or breastfeeding * Colorectal resection with concomitant hyperthermic intraperitoneal chemotherapy * Patient under long term corticosteroid therapy * Preoperative natremia \> 147 mmol/L * Hypokalemia (\< 3,3 mmol/L) * Patient with a contraindication to Methylprednisolone Mylan® : * Active infection * Active viral disease (namely hepatitis, herpes, varicella, shingles), * A psychotic condition that is not currently treated with medication, * Vaccination with a live vaccine or live attenuated within the last 3 months, * Hypersensitivity to methylprednisolone or to any of the excipients found in Methylprednisolone Mylan®