This study evaluates SPECT image data acquired from Spectrum Dynamics' multi-purpose CZT SPECT-CT camera. All subjects will undergo routine clinical Anger SPECT imaging and an additional SPECT acquisition on the CZT SPECT camera. Additionally some subjects will undergo CT on the CZT SPECT-CT camera. The quality of images from each device will be compared.
The Spectrum Dynamics Multi-purpose CZT SPECT camera is a whole body SPECT (single photon emission computed tomography) scanner which utilises solid-state cadmium zinc telluride (CZT) detectors to visualise injected, or otherwise introduced, radioactivity in the human body. The CZT SPECT camera detects the location and distribution of gamma-emitting radionuclides in the body and produces 3 dimensional cross-sectional images through computed reconstruction of the data for the purpose of determining various metabolic and physiologic functions in the human body. In comparison to conventional sodium iodide (NaI) gamma camera (or Anger camera) technology, solid state CZT technology offers improved energy, spatial and temporal resolution, and higher count rates. Improvements in energy resolution and sensitivity thus enable the potential capability for enhanced quantification, simultaneous dual isotope imaging and dynamic imaging acquisition. The camera system also incorporates a multi-slice CT gantry and acquired SPECT and CT images can be combined to improve image reconstruction by allowing fusion of CT and SPECT image data for anatomic localisation referencing and CT attenuation correction of the SPECT image data.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
140
Acquisition of SPECT (single photon emission computed tomography) imaging utilising a camera system with solid-state cadmium zinc telluride (CZT) detectors to visualise injected, or otherwise introduced, radioactivity in the human body.
CHU de Caen
Caen, Normandy, France
CZT SPECT Image Acquisition
Technical adequacy of acquired CZT SPECT images for demonstrating the location and distribution of gamma ray radionuclides within the body
Time frame: 1 day
CZT SPECT-CT Image Acquisition
Technical adequacy of acquired CZT SPECT-CT images for demonstrating the location and distribution of gamma ray radionuclides within the body
Time frame: 1 day
CZT SPECT Image Quality
Quality of acquired SPECT images from the CZT SPECT camera
Time frame: 1 day
Comparative Quality of CZT and Anger SPECT Images
Quality of acquired CZT SPECT images in comparison to the quality of images obtained from a conventional Anger gamma camera
Time frame: 1 day
Safety of the CZT SPECT Camera
Incidence of device related Adverse Events occurring during clinical use of the Spectrum Dynamics Multi-purpose CZT SPECT camera
Time frame: Through study completion; anticipated to be 24 months
Safety of the CZT SPECT Camera During Imaging Procedures
Incidence of peri-procedural Adverse Events
Time frame: 1 day
CZT SPECT-CT Image Quality
Quality of acquired SPECT-CT images from the CZT SPECT-CT camera
Time frame: 1 day
Comparative Quality of CZT SPECT-CT and Anger SPECT Images
Quality of acquired CZT SPECT-CT images in comparison to the quality of images obtained from a conventional Anger gamma camera
Time frame: 1 day
Safety of the CZT SPECT-CT Camera
Incidence of device related Adverse Events occurring during clinical use of the Spectrum Dynamics Multi-purpose CZT SPECT-CT camera
Time frame: Through study completion; anticipated to be 24 months
Safety of the CZT SPECT-CT Camera During Imaging Procedures
Incidence of peri-procedural Adverse Events
Time frame: 1 day
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