Comparison of Repeatability Between SS and SD-OCT for Measuring Retinal Thickness in Various Retinal Diseases

Hanyang University114 enrolled

Overview

Comparison of intradevice repeatability of thickness measurements for macular area in the eyes with normal and various retinal diseases using SS-OCT and SD-OCT

The investigators studied the intradevice repeatability of thickness measurements for total retina, retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform (GC-IPL) layers of macular area in the eyes with normal and various retinal diseases using SS-OCT and SD-OCT and compared the repeatability between two devices.

Study Type

OBSERVATIONAL

Enrollment

114

Conditions

Macula Abnormality

Interventions

Repeat exams of OCT deviceDEVICE

All 2 consecutive OCT examinations were performed by 1 experienced technician, in the order of SD-OCT and SS-OCT. The interval was 10 minutes between examinations by each OCT devices

Eligibility

Sex: ALLMin age: 19 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age-matched normal group was composed of subjects with age over at least 19 years, * a best-corrected visual acuity of 20/25 or higher, * normal fundus and intraocular pressure (IOP) \< 21mm Hg. Exclusion Criteria: * an spherical equivalent (SE) larger than ± 6 D, * cataract graded as more severe than grade 3 (Lens Opacities Classification System III), * a history of glaucoma and optic nerve diseases, or a history of vitrectomy.

Locations (1)

Hanyang University Guri Hospital

Guri-si, Gyeonggi-do, South Korea

Outcomes

Primary Outcomes

To compare repeatability between swept-source optical coherence tomography (SS-OCT) and spectral-domain OCT (SD-OCT) devices for the measurement of retinal thickness in various retinal diseases.

Comparison of Intraclass correlation coefficient (ICC) and coefficients of variability (CV) between devices

Time frame: Each device was examined twice consecutively within one minutes. After one OCT device exam, another OCT exam was performed immediately. The interval between test devices did not exceed 5 minutes.

Secondary Outcomes

To compare repeatability according to the degree of macular thickness

To compare the repeatability of retinal thickness according to central macular thickness in eyes with retinal diseases

Data from ClinicalTrials.gov

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