Investigating the Adhesion of New Adhesive to the Skin

Overview

The adhesion of the new adhesive strips is investigated on healthy volunteers

Inclusion visit: * Introduction to the study * Inclusion in study * Baseline information is obtained * Instruct subject to pre-strip of abdominal skin Test visits 1-25 (up to maximum 25 visits per subject. (1-3 days after pre-stripping the abdominal skin): * Baseline measurements are conducted on both sides of the stomach (TEWL, hydration, erythema, pH - 3 repeated measurements under each adhesive strip area (upper, middle and bottom of adhesive strip) * Potential wetting of skin - shower/bicycle exercise (max 60 minutes) and after-wetting baseline measurements are conducted (TEWL, hydration, erythema, pH - 3 times/strips (upper, middle and bottom of adhesive strip)) * Adhesive strips are weighted and applied * Potential shower/bicycle exercise (max 60 minutes) * Adhesive strips are removed at pre-defined timeslots (peel force measured) * Discomfort when strip was peeled of is evaluated by subject (VAS) * Measurements are conducted (TEWL, hydration, erythema, pH - 3 times/strips (upper, middle and bottom of adhesive strip)) * Acclimatization ½ * Measurements are conducted (TEWL, hydration, erythema, pH - 3 times/strips (upper, middle and bottom of adhesive strip)) * Adhesive strips are weighed * Photo of adhesive strips The subjects can be asked to apply and change strips every 24 hours between two test visits but for a maximum of 10 days between two visits. The strips should be applied at the same place every time.

Conditions

Interventions

Eligibility

Locations (1)

Outcomes