This study will assess the utility of different chlorhexidine mouthwash concentrations on ICU patients to decolonize their oral cavities from gram-negative bacteria, since this is a non-desirable condition that leads to higher mortality rates and longer hospitalization times. One group will receive the 0.12% chlorhexidine mouthwash and the other group will receive the 2% chlorhexidine mouthwash.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
74
Mouth Rinse with Chlorhexidine gluconate at 2% every 12 hours, one week.
Mouth Rinse with Chlorhexidine gluconate at 0.12% every 12 hours, one week.
University of Guanajuato
León, Guanajuato, Mexico
RECRUITINGGram-negative decolonization rate
Patients admitted to the ICU who were originally colonized with gram-negative bacteria and at the end of the study are no longer colonized by gram-negative bacteria.
Time frame: 2 weeks
Gram-negative colonization rate
Patients admitted to the ICU who were originally not colonized with gram-negative bacteria and at the end of the study are colonized by gram-negative bacteria.
Time frame: 2 weeks
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