Periodization of Exercise Training in Patients With Coronary Heart Disease.

Montreal Heart Institute70 enrolled

Overview

The research project includes two components that assess exercise physiology parameters, cerebrovascular reserve, cognitive functions and cardiac function in coronary heart disease patients at rest, during an acute exercise, and after two different periodized training programs.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Coronary Heart Disease Healthy Control

Interventions

Exercise trainingOTHER

Patients will undergo three weekly exercise training sessions with periodized high-intensity interval training and resistance training for a period of 12 weeks.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria for patients with coronary heart disease: * Major * Adequate physical and mental capacities * Autonomy in daily activities * Documented coronary artery disease * Stable or recent coronary artery disease Exclusion Criteria for patients with coronary heart disease: * Inability to complete the consent form * Acute coronary syndrome \< 3 months * Heart failure * Ejection fraction of the left ventricle \<40% * Coronary artery disease non revascularisable including left main coronary stenosis * Waiting for a bridging of the coronary artery * Chronic atrial fibrillation * Malignant arrhythmias during exercise * Restriction to non cardiopulmonary exercise * Severe intolerance to exercise

Locations (1)

Cardiovascular prevention and rehabilitation center

Montreal, Quebec, Canada

Outcomes

Primary Outcomes

Maximal oxygen uptake (VO2peak) with gas exchange

VO2peak will be measured during maximal exercise test with a gas exchange device. The highest value reached during the exercise phase of the maximal test (ergocycle) will be considered as the VO2peak. We will measure change of VO2peak before and after exercise training.