Meditative Slow Breathing or Isha Kriya Meditation in Improving Cancer-Related Symptoms in Hospitalized Participants With Cancer

M.D. Anderson Cancer Center41 enrolled

Overview

This trial studies how well meditative slow breathing or Isha Kriya meditation works in improving cancer-related symptoms in hospitalized participants with cancer. Meditative slow breathing or Isha Kriya meditation may help to decrease perceived stress and enhance well-being in hospitalized cancer participants.

PRIMARY OBJECTIVES: I. Test the feasibility of the meditation practice. SECONDARY OBJECTIVES: I. Explore the acceptability of meditation in cancer patients through modified Global Symptom Evaluation (GSE) and on day 7 +/- 1 day and day 28 +/- 3 days. II. Explore the effect of meditative practices in cancer patients through Edmonton Symptom Assessment Scale (ESAS) on the day of enrolment and a weekly basis until the end of study at four weeks. OUTLINE: Participants are randomized to 1 of 3 groups. GROUP I (MSB): Participants are instructed on the meditative slow breathing (MSB) technique and then perform MSB over 15 minutes twice daily (BID) for 28 days. GROUP II (IK MEDITATION): Participants are instructed on the 3 steps of Isha Kriya (IK) meditation and then perform IK meditation over 15 minutes BID for 28 days. GROUP III (WAITLIST): Participants are placed on a waitlist and receive standard supportive care for 28 days. After 28 days, participants may crossover to Group II.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Malignant Neoplasm

Interventions

Best PracticeOTHER

Receive standard supportive care

Meditation TherapyPROCEDURE

Perform MSB

Meditation TherapyPROCEDURE

Perform IK meditation

Questionnaire Administration

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of malignancy * Admitted to the hospital * Able to follow instructions * Eastern Cooperative Oncology Practice (Eastern Cooperative Oncology Group \[ECOG\]) score of 3 or below * Fluency in English Exclusion Criteria: * Patients with life expectancy less than 2 months per attending physician or advance practice provider's note or assessment of prognosis * Patients with cognitive dysfunction * Patients who are admitted for observation for \< 48 hours will be excluded from the study, as one day would be difficult to provide the necessary information * Patients who are delirious * Patients who are unable to follow instructions due to their medical condition * Patients admitted to the intensive care unit * Patients with ESAS \> 4/10 on dyspnea * Patients requiring oxygen more than 2 liters * Patients who are current meditation practitioners

Locations (1)

M D Anderson Cancer Center

Houston, Texas, United States

Outcomes

Primary Outcomes

Feasibility of the Meditation Practice defined by Recruitment Rate

Time frame: Day 7

Feasibility of the Meditation Practice defined by Adherence Rate

Time frame: Day 7

Secondary Outcomes

Acceptability of Meditation in Cancer Patients Assessed by Modified Global Symptom Evaluation (GSE)

Time frame: Day 7 and Day 28

Effect of Meditative Practices in Cancer Patients Assessed by Edmonton Symptom Assessment Scale (ESAS)

Scale is from 0 to 10 with 0 being no symptoms to 10 being worse symptoms. Proportions of participants who consider that the study makes their symptoms better estimated along with a 90% confidence interval for each of the intervention groups. The Linear mixed model used to examine the differential changes over time for ESAS scores among the three groups.

Time frame: Enrollment and a weekly basis until the end of study at four weeks.

Data from ClinicalTrials.gov

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