This is a Non-interventional, Multicenter study evaluating the efficacy and safety of the combination of pegylated liposomal doxorubicin and trabectedin in routine practice in patients with recurrent partial-platinum sensitive ovarian cancer, which is held in Kazakhstan.
Study Type
OBSERVATIONAL
Enrollment
60
Combination of Trabectedin + PLD: PLD 30 mg/m2 intravenous (IV) infusion over 90 minutes + trabectedin 1.1 mg/m2 IV infusion over 3 hours every 3 weeks.
Almaty oncological center
Almaty, Kazakhstan
RECRUITINGAlmaty regional oncological dispensary
Almaty, Kazakhstan
RECRUITINGObjective Response Rate (ORR)
ORR will be evaluated by Response Evaluation Criteria In Solid Tumors (RECIST V 1.1).
Time frame: Patient will be followed during 37 weeks
Progression-Free Survival (PFS)
PFS is defined as the time from the 1st treatment cycle until objective tumor progression or death
Time frame: Patient will be followed during 37 weeks
Safety according to CTCAE v4.0
To assess patient safety and the tolerance of trabectedin + PLD
Time frame: Patient will be followed during 37 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Kazakh institute of oncology and radiology
Almaty, Kazakhstan
Kazakh institute of oncology and radiology
Almaty, Kazakhstan
RECRUITINGAstana Oncology Center
Astana, Kazakhstan
RECRUITINGKyzylorda regional Oncological center
Kyzylorda, Kazakhstan
RECRUITINGWest Kazakhstan regional oncology dispensary
Oral, Kazakhstan
RECRUITINGNorth Kazakhstan Regional Oncology Center
Petropavl, Kazakhstan
RECRUITINGSouth Kazakhstan regional oncologic dispensary
Shymkent, Kazakhstan
RECRUITINGEast Kazakhstan Regional Oncology Dispensary
Ust-Kamenogorsk, Kazakhstan
RECRUITING