Enhanced automaticity process is the underlying mechanism for arrhythmias due to excess catecholamines. Catecholamines may increase in patients with PVC. Metabolites of catecholamines are metanephrine and normetanephrine. Our aim is to measure 24 hours urine levels of metanephrine and normetanephrine.
Premature ventricular complex is a very frequent arrhythmia. Suggested mechanisms for PVCs are reentry, triggered activity, and enhanced automaticity. Enhanced automaticity process is the underlying mechanism for arrhythmias due to excess catecholamines. Catecholamines may increase in patients with PVC. Half-lives of catecholamines are very short and rather changeable. Therefore, 24 hours urine levels of catecholamines are the more sensitive than plasma levels. Metabolites of catecholamines are metanephrine and normetanephrine. Our aim is to measure 24 hours urine levels of metanephrine and normetanephrine.
Study Type
OBSERVATIONAL
Enrollment
100
24 hours rhythm recording and 24 hours urine measurement
Erciyes university Yilmaz- mehmet öztaşkın heart hospital
Kayseri, Turkey (Türkiye)
metanephrine and normetanephrine levels
metanephrine and normetanephrine levels asociated premature ventricular complex frequents
Time frame: about 10 months
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