Effect of Composition and Timing of Ingestion of Fluids on the Urinary Excretion of Lithogenic Substances

Fondazione Policlinico Universitario Agostino Gemelli IRCCS12 enrolled

Overview

Interventional crossover study on healthy volunteers aimed at evaluating the effect of the composition and timing of ingestion of different types of water on the urinary excretion of lithogenic substances; the study will also analyze the effect of potassium citrate on urine pH and lithogenic substances

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Healthy

Interventions

WaterOTHER

1 liter of water in meals; 1 liter out of meals

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age \>18 years Exclusion Criteria: * Chronic malabsorption * Recurrent urinary tract infections * History of kidney stones

Locations (1)

Divisione di Nefrologia, Fondazione Policlinico Gemelli

Rome, Italy

Outcomes

Primary Outcomes

Urine composition

Time frame: Assessed the same day of water ingestion

Data from ClinicalTrials.gov

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