To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics.

Inclusion Criteria: 1. Documented cirrhosis with any underlying etiology 2. Hepatic encephalopathy of grade II and above 3. 18 to 65 years of age Exclusion Criteria: 1. Acute change in mental status due to a diagnosis other than hepatic encephalopathy 2. Patients who have received lactulose as an anticoma measure before enrollment 3. Patient who have developed encephalopathy post bleed 4. Patients with gut paralysis 5. Patients with tense ascites 6. Patients with altered sensorium due to organic brain disease. 7. Patients with coexistent psychiatric illness that may hamper the proper assessment of hepatic encephalopathy 8. Hemodynamic instability obviating vasopressors for resuscitation 9. Acute liver failure defined as severe acute liver injury with encephalopathy and international normalized ratio (INR)≥1.5 in a patient without pre-existing liver disease 10. Refusal of consent