Hypertensive disorders of pregnancy are important cause of severe morbidity, long-term disability and death among both mothers and their babies. In Africa and Asia, nearly one tenth of all maternal deaths are associated with hypertensive disorders of pregnancy research has focused on the antenatal complications' for both mother and baby and the risks and benefits of administering antihypertensive therapy prior to delivery hypertension disorders of pregnancy often persist following delivery and sometimes arise de novo postpartum one of the maternal complications of pre eclampsia is residual chronic hypertension in about 1/3 of cases elevated blood pressure is seen in 6%to 8% of all pregnancies hypertension (arterial pressure \>140/90 mmhg) in pregnancy is classified into one of four conditions 1. chronic hypertension that precedes pregnancy 2. pre eclampsia and eclampsia: a systematic syndrome of elevated arterial pressure,proteinuria and other findings 3. pre eclampsia superimposed upon chronic hypertension 4. gestational hypertension or nonproteinuric hypertension of pregnancy
Hypertensive disorders of pregnancy are important cause of severe morbidity, long-term disability and death among both mothers and their babies. In Africa and Asia, nearly one tenth of all maternal deaths are associated with hypertensive disorders of pregnancy research has focused on the antenatal complications' for both mother and baby and the risks and benefits of administering antihypertensive therapy prior to delivery hypertension disorders of pregnancy often persist following delivery and sometimes arise de novo postpartum one of the maternal complications of pre eclampsia is residual chronic hypertension in about 1/3 of cases elevated blood pressure is seen in 6%to 8% of all pregnancies hypertension (arterial pressure \>140/90 mmhg) in pregnancy is classified into one of four conditions 1. chronic hypertension that precedes pregnancy 2. pre eclampsia and eclampsia: a systematic syndrome of elevated arterial pressure,proteinuria and other findings 3. pre eclampsia superimposed upon chronic hypertension 4. gestational hypertension or nonproteinuric hypertension of pregnancy evaluate the effectiveness, safety and acceptability of Oral nifedipine versus oral labetalol in treatment of persistent postpartum hypertension
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
oral labetalol tablets and oral nifedipine tablets
Hossam Ahmed Abd Ellah
Asyut, Egypt
RECRUITINGcontrol blood pressure
duration,total dose to achieve blood pressure below the critical value between 140 and 150 mmHg systolic and 90-100 mmHg diastolic by monitoring of blood pressure
Time frame: till discharge of hospital about two days
Resolution of complications
Measured by monitoring of blood pressure and monitoring of the complications
Time frame: till discharge of hospital about two days
Improvement of hematological values
By repeated Complete blood count
Time frame: till discharge of hospital about two days
Side effects in both groups
Monitoring if there is any side effect of any drug
Time frame: till discharge of hospital about two days
Improvement of other investigations
Monitoring by repeated urine analysis,other investigations
Time frame: till discharge of hospital about two days
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