Incidence and Risk Factors of Central Line Catheter Related Thrombosis

Seoul National University Hospital80 enrolled

Overview

Central venous catheters are frequently used for monitoring haemodynamic status and rapidly delivering fluid therapy during the peri- and postoperative periods. Indwelling central venous catheters are typically used 7-14 days postoperatively for additional monitoring and treatment, but patients may develop asymptomatic catheter-related thrombosis, leading to life-threatening pulmonary embolism and death. Early detection helps to avoid such complications. This prospective observational study investigated the risk factors associated with catheter-related right internal jugular vein thrombosis in pediatric patients. The study enrolled 80 pediatric patients who were scheduled to receive central venous catheter. To detect thrombus formation, Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Central Line Complication

Interventions

ultrasound examinationOTHER

Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Eligibility

Sex: ALLMax age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * pediatric patients who were scheduled to catheterize central venous catheter Exclusion Criteria: * patients who had skin infections on the right side of the neck, making them unsuitable for placement of the catheter via the right side of the neck * patients who had blood coagulation lesions or bleeding tendencies * patients with thrombocytopenia * patients with a history of right internal jugular vein thrombosis * patients who presented right internal jugular vein thrombosis or stenosis on preoperative Doppler ultrasound examination

Outcomes

Primary Outcomes

thrombus formation using doppler ultrasound examination of internal jugular vein

Time frame: after central venous catheter placement and on each of the following days until the catheter was removed (maximum 5 days)