A retrospective study including 22 patients who have undergone amniotic membrane transplant in our unit up till 2016. Confocal microscopy and anterior segment optical coherence tomography (ASOCT) were performed to assess the retention of amniotic membrane and to detect any corneal structural changes. Comparison was made with 5 controls who had bullous keratopathy awaiting endothelial keratoplasty.
This retrospective cohort study (CREC Ref No.: CRE-2013.687) was approved by the Joint Chinese University of Hong Kong-New Territories East Cluster Clinical Research Ethics Committee. All patients who had AMT done due to symptomatic bullous keratopathy at the Prince of Wales Hospital and Alice Ho Miu Ling Nethersole Hospital (from 1998 onwards till June 2016) were invited back for confocal microscopy and anterior segment optical coherence tomography (ASOCT) at the clinic by the principal investigator (GS) from October to November 2016.
Study Type
OBSERVATIONAL
Enrollment
27
Amniotic membrane graft was transplanted onto the bullous cornea by the inlay technique
Amniotic membrane retention
Amniotic membrane retention in the cornea was assessed with confocal microscopy
Time frame: from date of operation till 2016
Pain
pain score (from 0-10, scale interval 1, 0 no pain, 10 most painful)reduction after amniotic membrane tranplant
Time frame: from date of operation till 2016
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.