Patients with Stage IV obstructing colorectal cancer and unresectable liver metastses, with general and local conditions not a risk for coliorectal resection, will be randomized to have either endoscopic stenting or colorectal resection
Patients with obstructing colorectal cancer, Stage IV with not resectable metastases will be considered . Patients with acceptable general and local conditions, to allow a safe surgical resection will be considered. Patients will be randomized to have endoscopic stenting or colorectal resection. All patients will receive postoperative chemio therapy
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
50
PLACEMENT OF AN ENDOSCOPIC SELF EXPANDABLE METAL STENT
Istituto Pietro Valdoni
Rome, Italy
RECRUITINGUniversity of Rome Sapienza
Rome, Italy
RECRUITINGMORTALITY
THE NUMBER OF POSTPROCEDURAL DEATHS
Time frame: 60 DAYS
SURVIVAL
SURVIVAL IN MONGTHS WILL BE DETERMINED FOR PATIENTS USING KAPLAN MEIER CURVES AND MEDIAN SURVIVAL
Time frame: 5 YEARS
POSTOPERATIVE MORBIDITY
MAJOR AND MINOR COMPLICATIONS AFTER THE PROCEDURE
Time frame: 60 DAYS
QUALITY OF LIFE
QUALITY OF LIFE WILL BE ASSESSED USING A STANDARDIZED PROTOCOL
Time frame: 5 YEARS
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