The Use of Perfusion CT Derived Parameters as Early Acute Pancreatitis Severity Biomarker Compared to Clinico Biological Score

Poitiers University Hospital15 enrolled

Overview

The investigators to establish whether early microvascular permeability parameter evaluated by perfusion-CT could be good biomarkers for severity in acute pancreatitis. Therefore the investigators want to compare 48 hours-clinico-biological systemic inflammatory response syndrome score to initial microvascular permeability parameters ( ktrans - capillary membrane permeability factor- and pancreatic blood flow ) calculated by OLEA software using inclusion perfusion CT.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Acute Pancreatitis

Interventions

Perfusion computed tomography.RADIATION

Using specific post treatment imaging software ( Olea® ) we will calculatell permeability parameters : the pancreatic blood flow and the k-trans, capillary membrane permeability factor.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient with acute pancreatitis (based on the Atlanta definition). Exclusion Criteria: * Patient under 18 yearras old * Contraindication of injection of iodinated contrast medium * Pregnancy

Locations (1)

Chu de Poitiers

Poitiers, France

Outcomes

Primary Outcomes

Relation between CT perfusion calculated k-trans and clinicobiological SIRS score in early phase of acute pancreatitis.

Time frame: admission day

Data from ClinicalTrials.gov

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