T-ICD vs S-ICD Shocks: Myocardial Injuries

Monaldi Hospital100 enrolled

Overview

Implantable cardioverter defibrillator (ICD) shocks are associated with a subsequent increased risk of death, and an elevation of cardiac enzymes has been measured after defibrillation testing (DFT). The aim of our study was to investigate the association between S-ICD vs T-ICD shocks and acute cardiac damage in humans, as evaluated by means of sensitive and highly specific circulating biomarkers

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

ICD Shock Myocardial Injuries

Interventions

ICDDEVICE

Implantable Cardioverter Defibrillator

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: patients who met the criteria for ICD implantation according to the current guidelines Exclusion Criteria: \-

Locations (1)

Monaldi Hospital

Naples, Italy

Outcomes

Primary Outcomes

myocardial micro-damage

degree of myocardial micro-damage, assessed by calculating the variation in the serum levels of high-sensitivity cardiac troponin I (hs-CTnI) and creatine kinase-MB mass concentration (CK-MB mass), measured before and after an S-ICD shock delivered during intraoperative DFT

Time frame: 6 months

Data from ClinicalTrials.gov

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