Oxygenation with high-flow nasal cannula with 100% oxygen have now been evaluated in a number of studies and the data are convincing. The THRIVE technique is able to oxygenate patients safely and vital parameters has been shown to be stable. But it is of great importance to evaluate this new concept regarding other potential negative physiological aspects such as lung atelectasis and inflammatory stress response before implementing it into clinical practice.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Oxygenation during apnea using transversal humidified oxygen
Ventilation during the procedure is governed by an endotracheal tube in the trachea and mechanical ventilation
Karolinska University Hospital
Stockholm, Sweden
Electrical impedans tomography
Changes in lung volumes
Time frame: baseline, intraoperative, 2 hours after start of intervention
Difference in Endtidal and arterial carbon dioxide partial pressure in the end of the procedure
Difference in Endtidal and arterial carbon dioxide partial pressure in the end of the procedure
Time frame: max 30 minutes after start of intervention
Increase in arterial carbon dioxide during the apnea
Measurement of arterial blood gases and here arterial carbon dioxide
Time frame: max 30 minutes after start of intervention
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