Prevalence of Sarcopenia and Undernutrition in Patients With Cirrhosis and Abdominal Hernia

University of Sao Paulo140 enrolled

Overview

The study evaluates whether sarcopenia influences the prevalence of abdominal hernias in patients with cirrhosis.

Sarcopenia is a common condition in patients with cirrhosis, with a prevalence of around 50%. It is unknown if the presence of sarcopenia may influence the prevalence of abdominal hernias in this group of patients. Clinical, nutritional and radiological evaluation will be performed in two groups of cirrhotic patients to evaluate this hypothesis.

Study Type

OBSERVATIONAL

Enrollment

140

Conditions

Cirrhosis Sarcopenia Malnutrition Hernia, Abdominal

Interventions

Computed Tomography ScanDIAGNOSTIC_TEST

The results of the CT scan and the hand-grip test will be used for diagnosis of sarcopenia. The Royal Free Hospital-Global Assessment (RFH-GA) results will classify the nutritional status of the patient.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ≥ 18 years * Previous diagnosis of cirrhosis Exclusion Criteria: * Acutely decompensated cirrhosis * Other chronic diseases in advanced stage (e.g. cardiac failure, chronic obstructive pulmonary disease, cancer) * Cognitive impairment, delirium, non-controlled psychosis

Locations (1)

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

Prevalence of Sarcopenia

Prevalence of Sarcopenia in patients with cirrhosis

Time frame: Through study completion (an average of 1 year)

Influence of Sarcopenia in Prevalence of Abdominal Hernias in Patients with Cirrhosis

Time frame: Through study completion (an average of 1 year)

Data from ClinicalTrials.gov

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