The aim of this study is to investigate the most effective stimulation site in transcranial direct current stimulation for gait recovery after stroke. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) bihemispheric stimulation - anodal stimulation on both ipsilesional and contralesional leg area of primary motor cortex and supplementary motor area. 2) ipsilesional stimulation - anodal stimulation on ipsilesional leg area of primary motor cortex and supplementary motor area. 3) contralesional stimulation - anodal stimulation on contralesional leg area of primary motor cortex and supplementary motor area. 4) sham stimulation. Subjects will walk on treadmill for 10 minutes during transcranial direct current stimulation. Motor evoked potential and functional evaluations will be done before and after stimulation to measure the changes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
24
anodal stimulation on Ipsilesional leg area of primary motor cortex and supplementary motor area for 30 minutes
anodal stimulation on contralesional leg area of primary motor cortex and supplementary motor area for 30 minutes
walking on treadmill for 10 minutes
Samsung Medical Center
Seoul, South Korea
Changes in motor evoked potential
measure the motor threshold and amplitude of motor evoked potential in tibialis anterior muscle.
Time frame: before and after intervention (approximately 30 minutes)
Changes in motricity index
measures motor function
Time frame: before and after intervention (approximately 30 minutes)
Changes in Fugl Meyer Assessment
Fugl Meyer Assessment is a measurement of motor function.
Time frame: before and after intervention (approximately 30 minutes)
Changes in 10 meter walking test
measures gait speed
Time frame: before and after intervention (approximately 30 minutes)
Timed up and go test
measures gait capacity and balance
Time frame: before and after intervention (approximately 30 minutes)
Functional ambulatory category
measure gait ability. 0 is impossible to gait and 6 is normal.
Time frame: before and after intervention (approximately 30 minutes)
Modified ashworth scale
measures spasticity with scale from 0 to 3. 0 is no increase in muscle tone. 3 is considerable increase in muscle tone, passive movement difficult.
Time frame: before and after intervention (approximately 30 minutes)
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