To evaluate the long-term outcome of chronic total occlusion (CTO) patients underwent contemporary percutaneous coronary intervention (PCI) techniques, we design this single-center, large-sample, prospective registry with five-year clinical follow-up, based on the intravascular ultrasound (IVUS) finding.
The study plan to include the patients with a CTO lesion in one of the three main epicardial coronary artery (diameter more than 2.5 mm) as the only target lesion. The CTO lesion is defined as 0 grade of thrombolysis in myocardial infarction (TIMI) flow with evidence of occlusion duration more than 3 months. All the PCI procedure will be performed by a group of certified operators in Fuwai Hospital, Beijing, China. All patients evaluate IVUS with automatic pullback (Opticross, Boston Scientific, US) performed after wire crossing. All the included patients are planned for five-year follow-up.
Study Type
OBSERVATIONAL
Enrollment
5,000
Lei Song
Beijing, Beijing Municipality, China
Target vessel revascularization
Any ischemic driven revascularization of the target vessel
Time frame: 5-year follow-up after index PCI
All-cause death
Any cause of death
Time frame: Within the first 1 month after PCI and during the 5-year follow-up
Cardiac death
Cardiac death
Time frame: Within the first 1 month after PCI and during the 5-year follow-up
Myocardial infarction
Any myocardial infarction including perioperative MI
Time frame: Within the first 1 month after PCI and during the 5-year follow-up
Stroke
Ischemic or hemorrhagic stroke
Time frame: Within the first 1 month after PCI and during the 5-year follow-up
Major adverse cardiac and cerebrovascular events (MACCE)
Including all-cause death, myocardial infarction, stroke or any target vessel revascularization
Time frame: Within the first 1 month after PCI and during the 5-year follow-up
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