Best Cutoff Value of Lactate Concentration in Vaginal Fluid to Predict Time of Spontaneous Onset of Labor in PPROM

Mennatallah Mohamed Elnemr42 enrolled

Overview

The present study is aimed to assess whether lactate determination in vaginal fluid is associated with and can predict onset of labor for women with suspected preterm prelabor rupture of membranes (PPROMs).

Study design: Prospective observational cohort

Study Type

OBSERVATIONAL

Enrollment

Conditions

Aim is to Investigate Association Between Lactate Concentration in Vaginal Fluid and Time of Spontaneous Onset of Labor in PPROM

Interventions

Lactate concentration in vaginal fluidDIAGNOSTIC_TEST

Lactate concentration in vaginal fluid

Eligibility

Sex: FEMALEMin age: 25 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 25-35 years old * BMI 25-30 * Singleton pregnancy in presentation with a history of suspected PPROM * A live fetus with gestational age between 26+0 weeks and 34+0 weeks Exclusion Criteria: * Abruption placenta * Medical disorders and hypertensive disorders of pregnancy * Intrauterine fetal death * Known or suspected fetal anomalies * Signs of infection (Fever, increase total leucocytic count) * Multiple pregnancy. * Regular uterine contractions. * History of cervical insufficiency

Locations (1)

Ain shams

Cairo, Egypt

Outcomes

Primary Outcomes

Time from examination to spontaneous onset of labor

Time from examination to spontaneous onset of labor \< or \> 48 hours according to concentration of lactate in vaginal fluid

Time frame: 48 hours

Data from ClinicalTrials.gov

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