Women often experience pain and discomfort during colposcopic examination especially at time of colposcopic directed excisional biopsy, pre-procedure anxiety, women pain threshold may also increase pain, woman's cooperation during the procedure is affected by all these factors, which also may hinder the colposcopist from obtaining adequate data and biopsies. Several pharmacological and non-pharmacological methods have been studied to reduce pain associated colposcopic directed biopsy (CDB). We aim to study the effect of Celecoxib to reduce pain associated with CDB.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
170
oral capsule 3 hours before procedure
Patient is placed in the lithotomy position. Vulva is examined for any suspicious lesions. A sterile bivalve speculum is introduced into the vagina to inspect cervix. A 3% acetic acid solution is applied to the cervix to map acetowhite areas for colposcopic directed punch biopsy using Tischler punch forceps.
oral capsule 3 hours before procedure
Cairo University
Cairo, Egypt
Pain during the procedure
Visual analog score in mm on a 10 cm ruler
Time frame: Immediately after the first biopsy
Pain at time of vaginal speculum application
Visual analog score in mm on a 10 cm ruler
Time frame: At time of introduction of vaginal speculum
Post-procedure pain
Visual analog score in mm on a 10 cm ruler
Time frame: At 30 minutes after completing the procedure
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