Role of Dopamine Transporter in Glucose Control

Pusan National University Hospital40 enrolled

Overview

Healthy subjects will be enrolled in this study. Each subject will be scanned twice with F18-FP-CIT PET which is commercially available. F18-FP-CIT reflects dopamine transporter availability of striatum. Before each PET scan, subject will be injected either glucose or normal saline. Therefore, PET scan will reflect the changes of dopamine transporter availability after the injection of glucose.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Obesity

Interventions

Glucose injection/Normal saline injectionOTHER

Before each PET scan, subject will be injected either glucose or normal saline.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy subjects Exclusion Criteria: * known neurologic disorder * known drug addiction * known endocrine disorder

Locations (1)

Pusan National University Hospital

Busan, South Korea

Outcomes

Primary Outcomes

Specific binding ratio of dopamine transporter availabilitiy measured from PET scans

Time frame: less than 1 month

Data from ClinicalTrials.gov

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