The purpose of this clinical study is to collect baseline information on dietary habits and metabolic risk factors, and to examine the effects of a dietary intervention focusing on fiber and antioxidant rich berries on the development of gestational diabetes, maternal glucose and lipid control and inflammation in obese pregnant women at risk of developing diabetes. With the ongoing epidemic of obesity, the prevalence of gestational diabetes is significantly increasing and the goal of this research is to identify optimal dietary strategies that can reverse this condition or control the rise in blood glucose among those with already developed diabetes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
34
Dietary frozen blueberries and soluble fiber for 20 weeks
University of Nevada at Las Vegas
Las Vegas, Nevada, United States
Gestational weight gain
Maternal weight gain in lbs
Time frame: 20 weeks
Gestational glycemia
Maternal blood glucose and HbA1c as measures of glycemia
Time frame: 20 weeks
Maternal serum lipids
Conventional total, LDL-cholesterol and their particle size to describe lipid profiles
Time frame: 20 weeks
Maternal inflammation
C-reactive protein as a stable biomarker of inflammation
Time frame: 20 weeks
Maternal biomarkers of atherosclerosis
Serum cytokines measured as interleukins and adipokines
Time frame: 20 weeks
Maternal dietary intakes
Maternal intakes of energy intake and nutrients
Time frame: 20 weeks
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