A study of two ventilatory strategies for low tidal volume ventilation compared to a control group to elucidate if low tidal volumes of 3ml/kg or 4ml/kg were feasible for one lung ventilation.
This study investigated the feasibility of low tidal volume ventilation for one lung ventilation. 45 patients were recruited - 15 patients in each of three groups, 3ml/kg, 4ml/kg or usual care. Outcomes studied were length of stay, 30 day mortality, unplanned ICU admission, evidence of respiratory failure or requirement for non-invasive ventilation, chest x-ray infiltrates and requirement for antibiotics.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
45
low tidal volume ventilation
St James's Hospital Dublin
Dublin, Ireland
Radiological evidence of injury to the ventilated lung
evidence of infiltrates in the non operative lung
Time frame: post operatively up to 6 weeks post operatively
unplanned ICU admission
unplanned admission to the icu with respiratory issues
Time frame: up to 6 weeks post operatively
Requirement for non-invasive ventilation
whether a patient in the trial requires niv for respiratory failure
Time frame: up to 6 weeks post operatively
Hospital acquired pneumonia
pneumonia acquired in hospital
Time frame: up to discharge at 6 weeks post operatively
length of hospital stay
number of days in hospital
Time frame: until patient discharge at 6 weeks post operatively
length of icu stay
number of days in ICU
Time frame: until patient discharge at 6 weeks post operatively
30 day mortality
number of patients who died within 30 days of their procedure
Time frame: 30 days post operatively
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