The purpose of the study is to compare dietary habits after bariatric surgery in patients with poor weight loss versus good weight loss outcomes.
The obesity epidemic is a major public health concern with a significant economic burden in the USA. Bariatric surgery is the most effective and durable weight loss treatment, with long-term cardiometabolic health benefits. Among different types of bariatric procedures, sleeve gastrectomy (SG) has become the most commonly performed in USA. While SG is expected to result in a 50-60% excess weight loss, inter-individual differences in weight loss are large and approximately 25% of patients can be considered poor weight-loss responders who either do not lose a substantial amount of weight or regain the lost weight afterwards. The mechanisms underlying this clinical variation remain unknown and interventions to improve on these outcomes critically lacking. Of interest, altered daily dietary habits are experienced by a substantial proportion of bariatric surgery candidates, raising the question whether such alterations may contribute to inter-individual differences in weight loss success. Therefore, the purpose of the study is to compare dietary habits after bariatric surgery in patients with different weight loss outcomes.
Study Type
OBSERVATIONAL
Enrollment
44
Participants will stay in the laboratory for two days and one night during which they will complete questionnaires, have blood drawn, and have other measurements taken.
Brigham and Women's Hospital
Boston, Massachusetts, United States
Self-rated hunger
Hunger measured from the visual analogue scale (VAS) questionnaire
Time frame: One day of laboratory protocol
Self-rated appetite
Appetite measured from the visual analogue scale (VAS) questionnaire
Time frame: One day of laboratory protocol
Appetite-regulating hormones
Appetite-regulating hormones from blood samples
Time frame: One day of laboratory protocol
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