To develop an experimental model of dyspnea by external thoraco-abdominal elastic strapping at rest in order to study the mechanisms involved in the relief of dyspnea by the administration of high flow by nasal cannula (HFNC).
This study will measure the effect of HFNC on an experimental model of dyspnea induced by thoraco-abdominal elastic strapping on healthy subjects at rest. The study will also compare the effects on dyspnea of the administration of high flow nasal cannula with and without oxygen added.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
32
Respiratory gaz heated and humidified system of delivery with a fraction of oxygen inspired of 100%
Respiratory gaz heated and humidified system of delivery with a fraction of oxygen inspired of 21%
Laboratoire de Physiopathologie Respiratoire du Service de Pneumologie et de Réanimation
Paris, France
Service de Pneumologie et Réanimation Médicale
Paris, France
Effects of high flow nasal cannula on strapping induced type of dyspnea
Evaluated by visual annylogic scale
Time frame: One hour
Compare the effect of the high flow by nasal cannula with and without oxygen on an experimental dyspnea, evaluated by the differences of changes in the visual analogic scale
Evaluated by visual annylogic scale
Time frame: One hour
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