Touchscreen-based Cognitive Tests in Healthy Volunteers

Inclusion Criteria: * Healthy Caucasian men aged 20-40 years * Body weight 50-100 kg * Body mass index 19-26 kg/cm2 * Normal physical examination including heart rate (HR; 50-90/min) blood pressure (BP; diastolic 65-90 and systolic 110-140) normal haematological and clinical chemistry variables normal ECG as judged by the investigator Exclusion Criteria: * Visual disability or red-green color blindness * History of mental health disorders as determined by self-reported a) physician-determined diagnoses of mental health disorders, except for nicotine and caffeine dependence, or history of suicide attempt; b) medications for mental health disorders * History of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, or neurological disorder * History of orthostatic syncope * History of head injury with sequelae * First-degree relative with a history of psychosis or epilepsy/seizure disorder or of a condition with risk of seizures * Current regular medication * Vaccination 2 weeks prior to study or during the study * Known or suspected allergy/hypersensitivity to any drug * History of regular alcohol consumption * Current substance dependence (excluding nicotine and caffeine). * Use of tobacco- or nicotine-containing products in excess of the equivalent of 5 cigarettes per day * Use of any medication or alcohol 24 hours before each study visit * Education less than high school * Clinically relevant symptoms of depression, anxiety or sleep disturbances * Donation of blood within 1 month prior to study * Participation in any study with an investigational product within 2 months prior to study * Clinical signs of suicidal or violent behaviour or psychotic symptoms