Contrast Nephropathy in Type 2 Diabetes

Fayoum University40 enrolled

Overview

To study the effect of radiocontrast material on kidney functions in diabetics with microalbuminuria

Study design: This study will be an observational prospective cohort study. Study population: Diabetics undergoing any intervention using radiocontrast material for any medical indication in Fayoum universiy hospital will be selected. There will be two arms of the study,each arm will contain 20 patients first arm diabetics on linagelptin, second arm diabetics on other DPP4 inhibitors. Data collection: Patients will be subjected to; full clinical examination,waist hip ratio assessment,BMI assessment fasting blood glucose,Serum uric acid, urine ACR, eGFR will be done before and after the investigation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Kidney Function Affection Upon Exposure to Radiocontrast Diabetes Microalbuminuria

Interventions

Linagliptin Oral TabletDRUG

Linagliptin for blood glucose control

Eligibility

Sex: ALLMin age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diabetics on DPP 4 inhibitor treatment Exclusion Criteria: * Diabetics on insulin

Locations (2)

Faculty of medicine Fayoum univesity

Al Fayyum, Egypt

Fayoum University

Al Fayyum, Egypt

Outcomes

Primary Outcomes

affection of estimated glomerular filtration rate

A significant decrease in estimated glomerular filtration rate (eGFR)

Time frame: Two months

Secondary Outcomes

change in serum uric acid

A significant rise in serum uric acid

Time frame: Two months

Data from ClinicalTrials.gov

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