Pre-gestational performance of hysterosalpingography (HSG) using an oil-soluble iodinated contrast medium has been demonstrated to be the main cause of excessive iodine exposure for pregnant women. However, its long-term health effects on the mothers and offsprings have not been adequately elucidated. A case registry study is designed to follow up all the pregnant women with pre-gestational history of ethiodized-oil HSG examination and try to keep track of maternal and fetal outcomes.
Study Type
OBSERVATIONAL
Enrollment
195
In this case registry study (observational study),all intervention will be performed not for research purposes, but only part of routine treatment, which will be recorded in database of the registry study.
comprehensive pregnant outcomes_prevalence of gestational diabetes
prevalence of gestational diabetes
Time frame: during the whole pregnancy, from date of verification of pregnancy until the date of termination of pregnancy, assessed up to 10 months
comprehensive pregnant outcomes_prevalence of gestational hypertension
prevalence of gestational hypertension
Time frame: during the whole pregnancy, from date of verification of pregnancy until the date of termination of pregnancy, assessed up to 10 months
comprehensive pregnant outcomes_prevalence of abnormal pregnancy
prevalence of abnormal pregnancy (stillbirth, abortion, premature delivery)
Time frame: during the whole pregnancy, from date of verification of pregnancy until the date of termination of pregnancy, assessed up to 10 months
comprehensive pregnant outcomes_rate of cesarean section
rate of cesarean section
Time frame: at the time of delivery
comprehensive neonatal outcomes at delivery
Apgar scores of neonates
Time frame: at the time of delivery
comprehensive neonatal outcomes_neonatal weight
birth weight of neonates
Time frame: at the time of delivery
comprehensive neonatal outcomes_neonatal head circumference
head circumference of neonates
Time frame: at the time of delivery
comprehensive neonatal outcomes_neonatal height
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height of neonates
Time frame: at the time of delivery
comprehensive neonatal outcomes_neonatal BMI
BMI of neonates
Time frame: at the time of delivery
comprehensive neonatal outcomes_prevalence of macrosomia or underweight
prevalence of macrosomia or underweight
Time frame: at the time of delivery
offspring outcomes_prevalence of thyroid dysfunction
prevalence of thyroid dysfunction (hyperthyroidism or hypothyroidism)
Time frame: from birth to age of 1 year old, assessed every 6 months
offspring outcomes_neurodevelopment evaluation in long term
Norwegian version of the Ages and Stages Questionnaire (ASQ) scores for evaluation of infant neurodevelopment
Time frame: from birth to age of 1 year old, assessed every 6 months
comprehensive offspring outcomes in long term - weight evaluation
weight of offsprings
Time frame: from birth to age of 1 year old, assessed every 3-6 months
comprehensive offspring outcomes in long term - height evaluation
height of offsprings
Time frame: from birth to age of 1 year old, assessed every 3-6 months
comprehensive offspring outcomes in long term - BMI evaluation
BMI of offsprings
Time frame: from birth to age of 1 year old, assessed every 3-6 months
prevalence of thyroid dysfunction in pregnancy
evaluation of maternal TSH, T3, T4, FT3, FT4, TRAb,Tg-Ab, TPO-Ab
Time frame: during the whole pregnancy, from date of verification of pregnancy until the date of termination of pregnancy, assessed up to 10 months
prevalence of iodine overload in neonates
prevalence of infants with urinary iodine concentration ≥200μg/L
Time frame: within 1 week after birth of neonates