Trans-aortic Valve Replacement and Renal Infarction

Sheba Medical Center20 enrolled

Overview

Kidney Magnetic Resonance assessment before and after undergoing transcatheter aortic valve replacement

Each patient will undergo Magnetic Resonance assessment of the kidneys before the TAVR. on the third to 7th day after the ATVR, a second MRI to the kidneys will be performed. we will assess the changes and new lesions between both MRI tests and will perform a qualitative and quantitative measurement.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Renal Infarction

Interventions

Magnetic Resonance test for kidneyDIAGNOSTIC_TEST

Magnetic Resonance test for kidney

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Severe symptomatic aortic stenosis * Patient is able to lay down supine for 20 min (the time needed to perform the MRI) without any difficulties. Exclusion Criteria: * Patient is on chronic renal replacement therapy (Dialysis) * Documented Thrombus in the left ventricle or left atria

Locations (1)

Sheba Medical Center

Ramat Gan, Israel

RECRUITING

Outcomes

Primary Outcomes

New Renal Infarction

New low signal intensity lesions on diffusion weighted images on MRI.

Time frame: one year

Secondary Outcomes

Hematuria

New hematuria on urine test.

Time frame: one year

Elevation in Blood Pressure

Delta of more than 5%

Time frame: one year

Elevation in Plasma Renin Activity

Delta of more than 5%

Time frame: one year

Elevation in Aldosteron level

Delta of more than 5%

Time frame: one year

Central Contacts

Arwa Younis, Doctor

CONTACT

0544731936 or.younis@gmail.com

Data from ClinicalTrials.gov

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