Seoul National University Pituitary Disease Cohort Study

Seoul National University Hospital1,600 enrolled

Overview

The purpose of this study is to investigate the treatment and natural history of pituitary disease. We have a longstanding interest in pituitary disease including acromegaly, central diabetes insipidus, and nonfunctioning pituitary adenoma. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to pituitary disease.

Subjects for this study will be recruited if they are: 1. Adults, male or female aged 18 years or older 2. Have been diagnosed with pituitary diseases

Study Type

OBSERVATIONAL

Enrollment

1,600

Conditions

Pituitary Disease Pituitary Incidentaloma Acromegaly Central Diabetes Insipidus Pituitary Stalk Compression Hyperprolactinaemia Cushing's Disease Pituitary Tumor

Interventions

Dynamic hormone study and Magnetic resonance imagingOTHER

1. Medical history 2. Imaging examination including brain magnetic resonance imaging 3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects for this study will be recruited if they are: 1. Adults, male or female aged 18 years or older 2. diagnosed with pituitary diseases such as acromegaly, Cushing's disease, hyperprolactinemia, nonfunctioning pituitary adenoma, pituitary stalk lesions, central diabetes insipidus, and craniopharyngiomas Exclusion Criteria: * Patients who do not agree with the study

Outcomes

Primary Outcomes

Treatment outcome of pituitary diseases

Remission rate

Time frame: Up to 10 years

Secondary Outcomes

Complications of pituitary disease

Visual field defect or hypopituitarism, hormone hyperfunction-related complications