tDCS in Patients With Disorders of Consciousness

First Affiliated Hospital of Zhejiang University

Overview

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Neurostimulation techniques such as deep brain stimulation (DBS) and spinal cord stimulation (SCS) have been used to treat DOC. Although these techniques have been shown to increase patient response, there are still some limitations. For example, DBS requires craniotomy and may increase the risk of intracranial hemorrhage and infection. In addition, the complexity and cost of these technologies also limit their potential applications.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Conditions

Consciousness Disorder Transcranial Direct Current Stimulation

Interventions

transcranial direct current stimulationDEVICE

the treatment of transcranial direct current stimulation

Eligibility

Sex: MALEMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients with DOC: VS and MCS (the cause of unification is: traumatic brain injury, the course of more than 1 month, not more than 1 year ; age 18-65; Past history without a mental disorder; No previous alcohol or substance abuse; No epilepsy or frequent spontaneous movement; No benzodiazepines; No moderate or severe hydrocephalus, All patients were right handed. Exclusion Criteria: Exclusion of organic heart disease, such as sinus bradycardia, arrhythmia; exclusion of patients with intracranial metal devices, pacemakers or any other device.

Locations (1)

The First Affiliated Hospital, Zhejiang University

Hangzhou, Zhejiang, China

Outcomes

Primary Outcomes

improvement of CRS-R

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Time frame: 7 days

Data from ClinicalTrials.gov

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