Dual-task Assessment and Rehabilitation for Individuals With Residual Symptoms After mTBI

Allina Health System24 enrolled

Overview

This research aims to develop an intervention that combines mTBI-specific motor and cognitive challenges into a progressive and challenging rehabilitation program. We plan to develop and refine a combined motor and cognitive intervention using healthy athletic young adults (n=12) and people with a positive history of non-resolving mTBI (n=12). We will conduct limited feasibility testing by conducting 6 week training sessions with each subject group. We also plan to identify best measures for determining readiness for duty or full function by incorporating and testing 3 dual-task assessment measures using state-of-the-art wearable sensors to quantify movement.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Brain Injury Traumatic Mild Concussion, Brain

Interventions

The intervention will take place 3 times per week for 6 weeks (60 minutes/session) and employs motor and cognitive challenges. It is based on known motor and cognitive deficits after mTBI and is structured using a theoretical framework published in another domain of neurologic disease. The intervention will consist of 6 stations that target known motor and cognitive impairments after mTBI. Each station will have 3 levels of difficulty with optional cognitive progressions. Subjects will spend 8 minutes at each station with a 2 minute transition/rest period between stations and will be progressed in motor and cognitive difficulty as able.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion criteria-healthy control: * Adults aged 18-34 years of age. * Strong history of athletic participation including high school and collegiate varsity and/or club sports * Current sport or recreational sport participation at least 3 days per week * Willingness to participate in 3 times a week 60 minute exercise program conducted at Courage Kenny Research Center (CKRC). Exclusion Criteria-healthy control: * History of concussion. * History of orthopedic or neurologic diagnosis (stroke, multiple sclerosis, Parkinson's Disease, etc.) interfering with subject's ability to exercise * Unwilling to exercise. * At risk for cardiopulmonary disease as defined by the American College of Sports Medicine. * Active medical contraindications by self-report after explanation of dual-task exercise program. * Active chemical dependency or major psychiatric disorders (ie., schizophrenia, major psychosis) by self-report. Inclusion criteria-subjects with mTBI residual symptoms: * Adults aged 18-50 years of age. * Self-report of some consistent exercise or activity a minimum of 2-3 days per week. * 3 weeks to 24 months post most recent concussion seeking treatment at Courage Kenny Rehabilitation Institute (CKRI) clinics * Willingness to participate in 3 times a week 60 minute exercise program conducted at CKRC. Exclusion Criteria- subjects with mTBI residual symptoms: * History of orthopedic or neurologic diagnosis (stroke, multiple sclerosis, Parkinson Disease, etc.) interfering with subject's ability to exercise * Unwilling to exercise. * At risk for cardiopulmonary disease as defined by the American College of Sports Medicine. * Active medical contraindications by self-report after explanation of dual-task exercise program, * Active chemical dependency or major psychiatric disorders (ie., schizophrenia, major psychosis).

Outcomes

Primary Outcomes

Change in peak velocity turns during Instrumented Stand and Walk Test

Change in peak velocity during 180 degree turns during Instrumented Stand and Walk Test in single task (ST) and dual-task (DT) conditions. DT condition involves grid memorization task.