A total of 50 participants diagnosed with ACS (group A ticagrelor 180mg/d, n=25), group B (clopidogrel 75mg + rivaroxaban 5mg/ d, n=25)) were consecutively enrolled and treated with study drugs on top of aspirin (100mg/d) for 1 month. VerifyNow® and Global thrombosis test were performed at day 2 and 1 month after administration of study drugs. The investigators compared aspirin reaction unit (ARU) and P2Y12 reaction unit (PRU), occlusion time (OT) which reflects shear stress-induced thrombotic activity, and lysis time (LT) which showed endogenous lytic activity between the two strategies at both time points.
Study Type
OBSERVATIONAL
Enrollment
56
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Occlusion time
Global thrombosis test
Time frame: 1 month
Lysis time
Global thrombosis test
Time frame: 1 month
Occlusion time
Global thrombosis test
Time frame: Day 2
Lysis time
Global thrombosis test
Time frame: Day 2
P2Y12 reaction unit
VerifyNow test
Time frame: Day 2 and 1 month
Aspirin reaction unit
VerifyNow test
Time frame: Day 2 and 1 month
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