CGRP-induced Migraine Attacks in Patients Who Have Tried Anti-CGRP Monoclonal Antibody Treatment

Inclusion Criteria: * Diagnosis of migraine according to the international classification of headache disorders version 3-beta * Subject has tried anti-CGRP antibodies for migraine * Women of childbearing potential are on safe contraception Exclusion Criteria: * Women of childbearing potential who do not use contraception. Includes non-hysterectomized women who have not been menopausal for at least two years. Safe contraception includes condoms, intrauterine devices, p-pills, surgical sterilization or gestagen injections. * Daily drug intake apart from contraceptives and preventive medication for migraine. * Ingestion of any drug 4 half-lifes before study start apart from contraceptives. * Pregnant or breast-feeding women * Migraine on the study day or less than 48 hours before CGRP infusion. * A history of cardiovascular and/or cerebrovascular disease * Systolic blood pressure \>150 mmHg and/or diastolic blood pressure \> 100 mmHg on study day. * Systolic blood pressure \<90 mmHg and/or diastolic blood pressure \< 50 mmHg on study day. * A history of mental illness * A history of any illness or condition that is deemed relevant for participation by the investigator.