Magnetic Steering Improves Small Bowel Capsule Endoscopy Completion Rate

Zhuan Liao227 enrolled

Overview

Patients referred for magnetically controlled capsule endoscopy (MCE) in the participating center from June 2017 to November 2017 were prospectively enrolled. Magnetic steering of MCE was performed after standard gastric examination. Capsule endoscopy completion rate (CECR), gastric transit time (GTT), pyloric transit time (PTT) and rapid gastric transit rate (GTT ≤ 30 min) were compared with the historical control group enrolled from January 2017 to May 2017.

Background and aims: Capsule endoscopy is currently available as a noninvasive and effective diagnostic modality to identify small bowel abnormalities, while the completion rate ranged from 75.1% to 95.6%. A novel magnetically controlled capsule endoscopy (MCE) system could facilitate the capsule to pass through pylorus thereby reducing the gastric transit time (GTT). The investigators perform this study to determine the potential improvement in capsule endoscopy completion rate (CECR) under magnetic steering vs standard mode. Methods: Patients referred for magnetically controlled capsule endoscopy (MCE) in the participating center from June 2017 to November 2017 were prospectively enrolled. Magnetic steering of MCE was performed after standard gastric examination. Capsule endoscopy completion rate (CECR), gastric transit time (GTT), pyloric transit time (PTT) and rapid gastric transit rate (GTT ≤ 30 min) were compared with the historical control group enrolled from January 2017 to May 2017.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

227

Conditions

Capsule Endoscopy Small Bowel Disease

Interventions

magnetic steeringOTHER

The capsule was controlled to pass through the pylorus by magnet steering.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients aged over 18 * With gastrointestinal complaints * Scheduled to undergo a capsule endoscopy for both stomach and small bowel Exclusion Criteria: * No surgical condition or refusing abdominal surgery to take out the capsule in case of capsule retention * Implanted pacemaker, except the pacemaker is compatible with MRI * Other implanted electromedical devices or magnetic metal foreign bodies * Pregnancy or suspected pregnancy

Locations (1)

Shanghai Changhai Hospital

Shanghai, China

Outcomes

Primary Outcomes

CECR

Capsule endoscopy completion rate

Time frame: Two weeks

Secondary Outcomes

Diagnostic cases by MCE

Esophageal, gastric, small bowel and colon diseases diagnosed by MCE

Time frame: Two weeks

Transit time

Esophageal/gastric/pyloric/small bowel/total transit time

Time frame: Two weeks

Rapid gastric transit rate

Rate of patients with a gastric transit time of ≤ 30 min

Time frame: Two weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.