The purpose of the study is to test how dietary habit interventions affect patients weight loss outcomes after bariatric surgery.
The obesity epidemic is a major public health concern with a significant economic burden in the USA. Bariatric surgery is the most effective and durable weight loss treatment, with long-term cardiometabolic health benefits. Among different types of bariatric procedures, sleeve gastrectomy (SG) has become the most commonly performed in USA. While SG is expected to result in a 50-60% excess weight loss, inter-individual differences in weight loss are large and approximately 25% of patients can be considered poor weight-loss responders who either do not lose a substantial amount of weight or regain the lost weight afterwards. The mechanisms underlying this clinical variation remain unknown and interventions to improve on these outcomes critically lacking. Of interest, altered daily dietary habits are experienced by a substantial proportion of bariatric surgery candidates, raising the question whether such alterations may contribute to inter-individual differences in weight loss success. Therefore, the purpose of the study is to test how dietary habit interventions affect patients weight loss outcomes after bariatric surgery. Since this is a single blind study, the details of the dietary interventions cannot be released during recruitment stage, but will be made public once enrollment closes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
44
Patients will be given a personalized plan regarding their diet.
Brigham and Women's Hospital
Boston, Massachusetts, United States
Post-intervention change in self-rated hunger
Differences in self-rated hunger as measured from the visual analogue scale (VAS; 0-100 score with 0 as ''not at all'' and 100 as ''very much''/''extremely'') questionnaire at baseline and after the intervention
Time frame: Baseline and 4 weeks (post-intervention)
Change in caloric intake
Difference in caloric intake from baseline to post-intervention
Time frame: baseline and 4 weeks (post-intervention)
Change in energy expenditure
resting and postprandial energy expenditure measured by indirect calorimetry
Time frame: baseline and 4 weeks (post-intervention)
Change in glucose tolerance
Glucose response to mixed meal test
Time frame: baseline and 4 weeks (post-intervention)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.