Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage

Inclusion Criteria: 1. Age ≥ 18 years 2. Supratentorial intracerebral hemorrhage confirmed by brain CT scan 3. Functional independence prior to ICH, defined as pre-ICH mRS ≤ 1 4. NIHSS score ≥ 4 and GCS ≥ 6 upon presentation 5. Able to commence RIC treatment within 12 hours of stroke onset 6. Signed and dated informed consent is obtained. Exclusion Criteria: 1. Definite evidence of secondary ICH, such as structural abnormality, brain tumor, thrombolytic drug, and other causes 2. A very high likelihood that the patient will die within the next 24 hours on the basis of clinical and/or radiological criteria 3. Already booked for surgical treatment 4. Life expectancy of less than 90 days due to comorbid conditions 5. Severe hematologic disease 6. Concurrent use of anticoagulation drugs including Warfarin, dabigatran, rivaroxaban. 7. Concurrent use of glibenclamide or nicorandil 8. Any soft tissue, orthopedic, or vascular injury, wounds or fractures in healthy upper limb which may pose a contraindication for application of RIC 9. Severe hepatic and renal dysfunction 10. Platelet count \<100×10\^9/L 11. Coagulopathy defined as INR,APTT,and PT beyond the upper limit of normal range 12. Known pregnancy, or positive pregnancy test, or breastfeeding 13. Patients being enrolled or having been enrolled in other clinical trial within 3 months prior to this clinical trial 14. A high likelihood that the patient will not adhere to the study treatment and follow up regimen 15. Patients unsuitable for enrollment in the clinical trial according to investigators decision making.