The Brugada Syndrome: a Follow-up Study

Universitair Ziekenhuis Brussel150 enrolled

Overview

Although for many years the Brugada syndrome has been labelled as a purely electrical disease in the structurally normal heart, the evolution of imaging techniques has enabled the discovery of subtle morphofunctional alterations in some of the Brugada syndrome patients. We will use new echocardiographic techniques to assess cardiac function in these patients and new parameters will be evaluated for their prognostic value as risk stratificators.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Brugada Syndrome

Interventions

Transthoracic echocardiographyDIAGNOSTIC_TEST

Transthoracic echocardiography Blood sample with assessment of biomarkers

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18 years or older * Diagnosis of Brugada syndrome Exclusion Criteria: * history of pericarditis, ischemic heart disease, cardiomyopathy of any origin, structural heart disease, or any other channelopathy

Locations (1)

UZ Brussel

Jette, Brussels Capital, Belgium

RECRUITING

Outcomes

Primary Outcomes

Composed outcome of sudden cardiac death, appropriate ICD shock and witnessed ventricular fibrillation

Sudden cardiac death is death occuring within 24 hours after being seen in a healthy status or within 1 hour after initiation of symptoms.

Time frame: 6 years

Secondary Outcomes

Syncope

Loss of consciousness

Time frame: 6 years

Central Contacts

Esther Scheirlynck

CONTACT

esther.scheirlynck@uzbrussel.be

Data from ClinicalTrials.gov

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