The purpose and primary objective of this study is to determine if there is an association between enteral tube feed (TF) osmolality and diarrhea in critically ill patients. The investigators hypothesize that the administration of a TF formulation with high osmolality will cause more diarrhea than a TF formulation with a lower osmolality.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
60
Continuous enteral tube feeding according to a standardized calculation via nasojejunal tube.
Continuous enteral tube feeding according to a standardized calculation via nasojejunal tube.
University of Utah Health
Salt Lake City, Utah, United States
Incidence of diarrhea at 72 hours
Time frame: 72 hour
Incidence of diarrhea at 14 days
Time frame: 14 days
Mean frequency of diarrhea days
Time frame: 14 days
Total number of diarrhea days
Time frame: 14 days
Mean diarrhea scores
Hart and Dobb Diarrhea Scale (a tool based on consistency and size of each stool, with a sum of all stools in one day equaling the score for each day and a score of 12 or more indicates diarrhea)
Time frame: 14 days
Time at 75% or more of goal tube feeding rate
Time frame: 14 days
Incidence of hypokalemia
Time frame: 14 days
Incidence of perineal dermatitis
Time frame: 14 days
Number of Clostridium difficile assays sent
Time frame: 14 days
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