Plant Exosomes and Patients Diagnosed With Polycystic Ovary Syndrome (PCOS) 17

Inclusion Criteria: * Age 18-40 year * Patients must have a confirmed diagnosis of PCOS according to the Rotterdam Criteria. At least 2 of the following 3 characteristics must be present: 1. Oligo-anovulation 2. Clinical and/or biochemical signs of androgen excess and 3. Polycystic ovarian morphology (PCOM) (defined by an increased number of small antral follicles \[≥12 follicles that were \<10 mm in diameter\] or an increased individual ovarian volume \[\>10 cm3\] in 1 or both ovaries. Disorders mimicking PCOS must also be excluded, including thyroid dysfunction, hyperprolactinemia, late-onset congenital adrenal hyperplasia, and ovarian or adrenal androgen-producing tumors. * Of all subjects screened patients must be informed of the investigational nature of this study and give written informed consent in accordance with institutional and federal guidelines. * Ability to understand and willingness to sign a written informed consent document. * Absence of life limiting medical conditions Exclusion Criteria: * • Pregnancy * Known HIV * Patients receiving immunosuppressive drugs * Patients taking confounding medications such as sex steroids, infertility medications or insulin sensitizers or any medication deemed to alter glucose and/or insulin levels * Active malignancy in the last 5 years * Patients receiving any other investigational agent(s) * Ginger and/or aloe allergy