Synthetic MR Technologies has created a quantified imaging solution - SyMRI - to enable radiologists to acquire quantified images and always obtain the best contrast images. This study represents an attempt to assess the clinical utility of this software.
Typical magnetic resonance imaging (MRI) involves taking many images called 'contrasts' to look at the body in different ways. Standard scan settings are usually good enough for a radiologist to review. The best settings often change with the age of the patient and their health, and are time consuming to determine. Quantified imaging is an alternative to contrast-based imaging which explicitly measures tissue properties and can be used to create almost any contrast. This method of imaging has been held back by a lack of the right software. Synthetic MR Technologies has created a quantified imaging solution - SyMRI - to enable radiologists to acquire quantified images and always obtain the best contrast images. The objective of this study is to evaluate SyMRI in a pediatric population to determine if Sickkids would be interested in purchasing this product / support Health Canada approval. Specifically, the investigators are interested in determining if SyMRI is clinically useful: * Is synthetic imaging quality comparable / better than conventional imaging? * Qualitative - Are radiologists more confident using synthetic MR vs conventional * Quantitative - Signal-to-noise (SNR) and Contrast-to-noise (CNR) * To what extent can total exam times be reduced? * Is the software user friendly and would investigators use it?
Study Type
OBSERVATIONAL
Enrollment
5
The MDME sequence aims to provide whole absolute quantification of T1, T2, PD and B1 inhomogeneity in 5 minutes at typical clinical resolution (0.8 x 0.8 x 5mm). SyMRI software then allows a user to synthesize any almost image contrast (T1, T2, PD, FLAIR, IR, DIR, etc) by adjusting imaging parameters after the fact.
The Hospital for Sick Children
Toronto, Ontario, Canada
Diagnostic Quality relative to conventional imaging
Radiologist compares qualitative diagnostic quality of SyMRI imaging against Conventional Imaging. Measure - Poorer, Equal, Better
Time frame: Through study completion, an average of 1 year
Scan time for SyMRI vs Conventional MR
Compare acquisition time for SyMRI scans vs Conventional MR Measure - Minutes:Seconds
Time frame: Through study completion, an average of 1 year
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