Bacteriological Link Between Upper and Lower Airways in Cystic Fibrosis and Primary Ciliary Dyskinesia

N/ACompletedNCT03494894

Centre Hospitalier Intercommunal Creteil120 enrolled

Overview

Cytobacteriological examination of sputum and bacteriological sampling in the middle meatus.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Cystic Fibrosis Primary Ciliary Dyskinesia

Interventions

Middle meatus aspirations and sputumDIAGNOSTIC_TEST

Bacterial genotype sequencing analysis will be performed in patients with bacteriological concordance between upper and lower airways.

Eligibility

Sex: ALLMin age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over 6 years old * Patients with cystic fibrosis or primary ciliary dyskinesia. * Patients capable of performing an expectorations * Patients having been informed of the research, having received the information note and not having opposed the research Exclusion Criteria: \- Refusal to participate in the study

Locations (1)

Centre Hospitalier Intercommunal de Créteil

Créteil, France

Outcomes

Primary Outcomes

Presence of bacterial colonization of the upper and lower airway

Time frame: 1 day

Secondary Outcomes

bacteriological concordance

bacteriological concordance of upper airways (VAS) and lower (VAI) between patients with cystic fibrosis and those with primary ciliary dyskinesia.

Time frame: 1 day

bacteria genotype

Compare the genotype of bacteria present in both VAS and VAI.

Time frame: 1 day

bacteriological concordance in children

Subgroup analysis (group \<18 years old)

Time frame: 1 day

bacteriological concordance in adult

Subgroup analysis (adult group)

Time frame: 1 day

Data from ClinicalTrials.gov

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